RESEARCH FACULTY
李亮
副研究员 · 硕士生导师
自身免疫性肝病的区域与系统免疫
- 身份
- 科研骨干
- 研究方向
- 自身免疫性肝病的区域与系统免疫
PROFILE
个人简介
副研究员，硕士生导师。本科和博士毕业于中国科学技术大学。
以第一/通讯作者（含共同）在 Gut、Nat Commun、J Autoimmun 等杂志发表论文 16 篇，其中一篇被杂志选为当月 Highlight 论文；参与撰写英文专著《Liver Immunology: Principles and Practice》一章节。
主持国家自然科学基金面上项目等项目 6 项。
个人兴趣：平生最喜是田畴，一水一山皆可留
EDUCATION & CAREER
教育与工作经历
- 本科毕业于中国科学技术大学
- 博士毕业于中国科学技术大学
RESEARCH
研究方向
- 自身免疫性肝病的区域与系统免疫
GRANTS & SERVICE
主持项目与学术服务
主持项目
- 主持国家自然科学基金面上项目等项目 6 项
学术服务
- 担任 Signal Transduct Target Ther、Adv Sci、J Immunother Cancer、Phytomedicine 等杂志审稿人
SELECTED PAPERS
代表性论文
- Autophagy of Kupffer Cells Modulates CD8+ T Cell Activation in Primary Biliary CholangitisGut. 2026;75(9):1831-1844 · doi:10.1136/gutjnl-2025-335611 · PMID 41371935Pan-Yue Luo#, Min Ma#, Meng-Chu Liu#, Ye-Hui Wu, Jie Long, Meng-Xing Huang, Si-Yu Yang, Tian-Tian Da, Koichi Tsuneyama, Qiao Li, Haosheng Jin, Zhi-Bin Zhao, Jun Wang, Xiong Ma, M. Eric Gershwin, Ying Han*, Zhe-Xiong Lian*, and Liang Li*站内成果页 →
- Bone marrow CD8+ Trm cells induced by IL-15 and CD16+ monocytes mediate HSPC destruction in human severe aplastic anemiaJie Long#, Xing You#, Qiong Yang#, Song-Rong Wang, Ming Zhou, Wei Zhou, Caixia Wang, Huafeng Xie, Yuping Zhang, Shunqing Wang*, Zhe-Xiong Lian* and Liang Li*
- Lymphatic endothelial cell-mediated accumulation of CD177+ Treg cells suppresses antitumor immunity in human esophageal squamous cell carcinomaMin Ma#, Liang Li#, *, Shu-Han Yang, Chuan Huang, Weitao Zhuang, Shujie Huang, Xin Xia, Yong Tang, Zijun Li, Zhi-Bin Zhao, Qingyun Chen, Guibin Qiao* and Zhe-Xiong Lian*
- Targeting pathogenic CD8+ tissue-resident T cells with chimeric antigen receptor therapy in murine autoimmune cholangitisHao-Xian Zhu#, Shu-Han Yang#, Xiao-Min Chen, Rong-Rong Huang, Cai-Yue Gao, Qian-Li Meng, Xin Li, Haosheng Jin, Koichi Tsuneyama, Ying Han, Liang Li*, Zhi-Bin Zhao*, M. Eric Gershwin* and Zhe-Xiong Lian*站内成果页 →
- FoxO1 suppresses IL-10 producing B cell differentiation via negatively regulating Blimp-1 expression and contributes to allergic asthma progressionSong-Rong Wang#, Ren-Dong Hu#, Min Ma#, Xing You, Haiyan Cui, Yi He, Damo Xu, Zhi-Bin Zhao, Carlo Selmi, M. Eric Gershwin, Liang Li* and Zhe-Xiong Lian*
- Chromatin accessibility analysis identifies the transcription factor ETV5 as a suppressor of adipose tissue macrophage activation in obesityRen-Dong Hu#, Wen Zhang#, Liang Li*, Zu-Qi Zuo, Min Ma, Jin-Fen Ma, Ting-Ting Yin, Cai-Yue Gao, Shu-Han Yang, Zhi-Bin Zhao, Zi-Jun Li, Gui-Bin Qiao, Zhe-Xiong Lian* and Kun Qu*
- Immune Checkpoint Molecules. Possible Future Therapeutic Implications in Autoimmune DiseasesChuan Huang#, Hao-Xian Zhu#, Yuan Yao, Zhen-Hua Bian, Yu-Jian Zheng, Liang Li*, Haralampos Moutsopoulos, M. Eric Gershwin and Zhe-Xiong Lian*
- CD8+ T cells and IFN-γ induce autoimmune myelofibrosis in miceYuan Yao#, Liang Li#, Shu-Han Yang, Cai-Yue Gao, Liang-Huan Liao, Yu-Qing Xie, Xue-Ying Yin, Yan-Qing Yang, Yun-Yun Fei, Zhe-Xiong Lian*