SELECTED PUBLICATIONS

代表论文

围绕自身免疫、肝脏免疫、免疫代谢、单细胞空间组学与工程化免疫治疗的代表性研究。

2023—2026

精选近年来围绕自身免疫、肝脏免疫和转化治疗的研究成果

2026PBC · Kupffer cells

Gut

Autophagy of Kupffer cells modulates CD8+ T cell activation in primary biliary cholangitis

Pan-Yue Luo et al.
PubMed 记录 ↗

2025Gut–Liver Axis · Microbiome

Cell Host & Microbe

Cohabitation facilitates microbiome shifts that promote isoflavone transformation to ameliorate liver injury

Yan Zeng, Rui Wu, Yi He, et al.
PubMed 记录 ↗

2025Autoimmune Liver

Advanced Science

PD-1+CD8+ T cell-mediated hepatocyte pyroptosis promotes progression of murine autoimmune liver disease

Jie Long et al.
PubMed 记录 ↗

2025CAR-T · Sjögren disease

Arthritis & Rheumatology

Identification of Pathogenic PD-1+CD8+ T Cells for Effective Chimeric Antigen Receptor Therapy in a Murine Model of Sjögren Disease

Jin-Fen Ma et al.
PubMed 记录 ↗

2024Tfh · Autoimmunity

Immunity

Deficiency of CBL and CBLB ubiquitin ligases leads to hyper T follicular helper cell responses and lupus by reducing BCL6 degradation

Xin Li et al.
PubMed 记录 ↗

2024Immunometabolism · HCC

Journal of Hepatology

Targeting OXCT1-mediated ketone metabolism reprograms macrophages to promote antitumor immunity via CD8+ T cells in hepatocellular carcinoma

Chu-Xu Zhu et al.
PubMed 记录 ↗

2024CAR-T · PBC

Nature Communications

Targeting pathogenic CD8+ tissue-resident T cells with chimeric antigen receptor therapy in murine autoimmune cholangitis

Hao-Xian Zhu et al.
DOI 记录 ↗

2023Single-cell · Spatial

Science Advances

Single-cell and spatial transcriptome analysis reveals the cellular heterogeneity of liver metastatic colorectal cancer

Fei Wang et al.
PubMed 记录 ↗

2023Single-cell · Sjögren's

JCI Insight

Single-cell profiling reveals pathogenic role and differentiation trajectory of Granzyme K+CD8+ T cells in primary Sjögren's syndrome

Ting Xu et al.
PubMed 记录 ↗