EDUCATION & CAREER
教育与工作经历
- 2014.09 – 2020.12：中国科学技术大学，生物学博士（导师：裴端卿教授）
- 2011.09 – 2013.07：安徽师范大学，英语文学学士（辅修）
- 2010.09 – 2014.07：安徽师范大学，生物科学理学学士
RESEARCH
研究方向
- 细胞命运决定中的转录调控与表观遗传修饰
擅长实验技术
- 小鼠/人 iPS、干细胞分化、细胞转分化、基因编辑
- 细胞培养与谱系诱导、稳定细胞系构建（过表达/敲低/敲入/敲除）、化合物筛选
- 原代细胞分离（小鼠胚胎成纤维细胞、肝细胞、骨髓来源巨噬细胞等）
- 分子克隆、CRISPR-Cas9、基因分型、RT-qPCR、Western Blot、co-IP、免疫荧光、FACS
- RNA-seq / ATAC-seq / ChIP-seq 高通量测序
- 小鼠繁育与尾静脉注射
SELECTED PAPERS
代表性论文
- The nuclear factor CECR2 promotes somatic cell reprogramming by reorganizing the chromatin structureLinlin Wu#, Guoqing Zhao, Shuyang Xu, Junqi Kuang, Jin Ming, Guangmin Wu, Tao Wang, Bo Wang, Ping Zhu, Duanqing Pei*, Jing Liu*
- Induction of Pluripotent Stem Cells from Mouse Embryonic Fibroblasts by Jdp2-Jhdm1b-Mkk6-Glis1-Nanog-Essrb-Sall4Bo Wang#, Linlin Wu#, Dongwei Li#, Yuting Liu, Jing Guo, Chen Li, Yuxiang Yao, Yaofeng Wang, Guoqing Zhao, Xiaoshan Wang, Meijun Fu, He Liu, Shangtao Cao, Chuman Wu, Shengyong Yu, Chunhua Zhou, Yue Qin, Junqi Kuang, Jin Ming, Shilong Chu, Xuejie Yang, Ping Zhu, Guangjin Pan, Jiekai Chen, Jing Liu*, Duanqing Pei*
- Cell fate decision by a morphogen-transcription factor-chromatin modifier axisJin Ming#, Lihui Lin#, Jiajun Li, Linlin Wu, Shicai Fang, Tao Huang, Yu Fu, Dong Liu, Wenhui Zhang, Chen Li, Yongzheng Yang, Yi Huang, Yue Qin, Junqi Kuang, Xiangnan Huang, Liman Guo, Xiaofei Zhang, Jing Liu, Jiekai Chen, Chengchen Zhao*, Bo Wang*, Duanqing Pei*
- The NuRD complex cooperates with SALL4 to orchestrate reprogrammingBo Wang#, Chen Li#, Jin Ming#, Linlin Wu, Shicai Fang, Yi Huang, Lihui Lin, He Liu, Junqi Kuang, Chengchen Zhao, Xingnan Huang, Huijian Feng, Jing Guo, Xuejie Yang, Liman Guo, Xiaofei Zhang, Jiekai Chen, Jing Liu, Ping Zhu*, Duanqing Pei*
- SS18 regulates pluripotent-somatic transition through phase separationJunqi Kuang#, Ziwei Zhai#, Pengli Li, Ruona Shi, Wenjing Guo, Yuxiang Yao, Jing Guo, Guoqing Zhao, Jiangpin He, Shuyang Xu, Chuman Wu, Shengyong Yu, Chunhua Zhou, Linlin Wu, Yue Qin, Baomei Cai, Wei Li, Zichao Wu, Xiaoxi Li, Shilong Chu, Tingting Yang, Bo Wang, Shangtao Cao, Dongwei Li, Xiaofei Zhang, Jiekai Chen, Jing Liu*, Duanqing Pei*
- BMP4 resets mouse epiblast stem cells to naive pluripotency through ZBTB7A/B-mediated chromatin remodellingShengyong Yu#, Chunhua Zhou#, Shangtao Cao#, Jiangping He#, Baomei Cai, Kaixin Wu, Yue Qin, Xingnan Huang, Lizhan Xiao, Jing Ye, Shuyang Xu, Wenxiu Xie, Junqi Kuang, Shilong Chu, Jing Guo, He Liu, Wei Pang, Lin Guo, Mengying Zeng, Xiaoshan Wang, Rongping Luo, Chen Li, Guoqing Zhao, Bo Wang, Linlin Wu, Jiekai Chen, Jing Liu*, Duanqing Pei*
- Chemical reprogramming of mouse embryonic and adult fibroblast into endoderm lineageShangtao Cao#, Shengyong Yu#, Yan Chen, Xiaoshan Wang, Chunhua Zhou, Yuting Liu, Junqi Kuang, He Liu, Dongwei Li, Jing Ye, Yue Qin, Shilong Chu, Linlin Wu, Lin Guo, Yinxiong Li, Xiaodong Shu, Jiekai Chen, Jing Liu*, Duanqing Pei*